Guinea-Bissau 2-1 São Tomé and Príncipe in the World Cup Qual. CAF , Round 1.

São Tomé and Príncipe lost all 3 matches (L–L–L), scoring 1 and conceding 6.

The two sides have met 4 times: Guinea-Bissau 4 wins, São Tomé and Príncipe 0, 0 draws.